C14 studies of uric acid turnover.

Studies in Uric Acid Metabolism

Studies on Uric Acid and Related Compounds

The systematic study of the substrate specificity of mammalian xanthine oxidase has indicated a common mechanism by which various purines may be dehydrogenated (1). The results obtained also made it clear why methylated xanthines, with the exception of 1-methylxanthine (2), cannot be oxidized by xanthine oxidase to the corresponding substituted uric acids (3, 4). Therefore, another source had t...

Studies on leukemia. I. Uric acid excretion.

IT HAS BEEN KNOWN siunce 1870,t amid has siunce heems comnfirmnned miuamny tinses29 that the excretioun of uric acid nsay he increased imn sonic pat ients with leuukensia. This has not, horvever, heems ann euntirely consistennt fimndimigt4 8 am-id the possible reasouns for the differeusces imn uric acid excretiomn ansomug patients with leukemia have uot beets imnvestigated. Whether the uric aci...

Studies on uric acid and related compounds. I. Quantitative determination of uric acid in biological fluids.

The available methods of determination of uric acid can be divided into three main groups: (a) the direct determination of the reducing power of uric acid; (b) the coprecipitation of the uric acid or its adsorption on a precipitating material, dissolving the acid, and determination of its reducing power; and (c) quantitative decomposition of uric acid by uricase. A survey of these methods has b...

Metabolism of pyruvic acid-2-C14 and hydroxypyruvic acid-2-C14 in algae.

The metabolism of pyruvic acid in the light and dark by Scenedesmus has been examined with two aims: to study the relationship of its metabolism to that of the intermediates of C1402 fixation and to compare its metabolic fate with that of hydroxypyruvate. The metabolism of hydroxypyruvic acid was compared with that of C1402 fixation in order to ascertain whether it might be a photosynthetic int...